Publications

Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals

Lee, J.J., Wedow, R., Okbay, A. et al. Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals. Nat Genet 50, 1112–1121 (2018). https://doi.org/10.1038/s41588-018-0147-3

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Kunkle, B.W., Grenier-Boley, B., Sims, R. et al. Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nat Genet 51, 414–430 (2019). https://doi.org/10.1038/s41588-019-0358-2

Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder

Demontis, D., Walters, R.K., Martin, J. et al. Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder. Nat Genet 51, 63–75 (2019). https://doi.org/10.1038/s41588-018-0269-7

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

Wray, N.R., Ripke, S., Mattheisen, M. et al. Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression. Nat Genet 50, 668–681 (2018). https://doi.org/10.1038/s41588-018-0090-3

Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases

Verbanck, M., Chen, CY., Neale, B. et al. Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases. Nat Genet 50, 693–698 (2018). https://doi.org/10.1038/s41588-018-0099-7

Tumor mutational load predicts survival after immunotherapy across multiple cancer types

Samstein, R.M., Lee, CH., Shoushtari, A.N. et al. Tumor mutational load predicts survival after immunotherapy across multiple cancer types. Nat Genet 51, 202–206 (2019). https://doi.org/10.1038/s41588-018-0312-8

Epigenetic variation impacts individual differences in the transcriptional response to influenza infection

Aracena, K.A., Lin, YL., Luo, K. et al. Epigenetic variation impacts individual differences in the transcriptional response to influenza infection. Nat Genet 56, 408–419 (2024). https://doi.org/10.1038/s41588-024-01668-z

Genome assemblies of 11 bamboo species highlight diversification induced by dynamic subgenome dominance

Ma, PF., Liu, YL., Guo, C. et al. Genome assemblies of 11 bamboo species highlight diversification induced by dynamic subgenome dominance. Nat Genet (2024). https://doi.org/10.1038/s41588-024-01683-0

Subspecific origin and haplotype diversity in the laboratory mouse

Yang, H., Wang, J., Didion, J. et al. Subspecific origin and haplotype diversity in the laboratory mouse. Nat Genet 43, 648–655 (2011). https://doi.org/10.1038/ng.847

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Kunkle, B.W., Grenier-Boley, B., Sims, R. et al. Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nat Genet 51, 414–430 (2019). https://doi.org/10.1038/s41588-019-0358-2